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A sleeping person is unconscious. An unconscious person is helpless.
A helpless person has a dex of 0, and the equivalent modifier (-5).
An unconscious person is also considered willing for the purpose of "willing" spells. This is a small subset of spells though.
Lets assume someone has a Reflex save of 8 (from a base +3 and a Dex of 20, yielding +5, for the +8 total), a Will save of +4, and a Fort save of +4.
Case A:
If they are up and running around normally:
Fireball allows a reflex save of +8. The character may voluntarily give up the reflex save.
Slow allows a fort save of +4. The character may voluntarily give up the fort save.
Hold person allows a will save of +4. The character may voluntarily give up the will save.
Haste has the (harmless) tag. The character may voluntarily choose to make a fort save at +4, but ordinarily doesn't get one.
Teleport affects willing creatures. The character may choose to not be willing, in which case, they aren't affected.
Case B:
If the person is helpless, but conscious:
Fireball allows a reflex save of -2. The character may voluntarily give up the reflex save. The spell is at -2 because of the base +3 and the +5 from 20 Dex being replaced with -5 of 0 Dex.
Slow allows a fort save of +4. The character may voluntarily give up the fort save.
Hold person allows a will save of +4. The character may voluntarily give up the will save.
Haste has the (harmless) tag. The character may voluntarily choose to make a fort save at +4, but ordinarily doesn't get one.
Teleport affects willing creatures. The character may choose to not be willing, in which case, they aren't affected.
Case C:
If the person is unconscious, they are also helpless.
Fireball allows a reflex save of -2. The character must attempt the reflex save. The spell is at -2 because of the base +3 and the +5 from 20 Dex being replaced with -5 of 0 Dex.
Slow allows a fort save of +4. The character must attempt the fort save.
Hold person allows a will save of +4. The character must attempt the will save.
Haste has the (harmless) tag. The character may not choose to make a fort save.
Teleport affects willing creatures. The character is considered willing, because they are unconscious.
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